5. Analysis of feed forward loops

Design principles

  • The C1-FFL with AND logic has an on-delay, but no off-delay.

  • The C1-FFL with OR logic has an off-delay, but no on-delay.

  • The C1-FFL with both AND and OR logic can filter out short input impulses.

  • The I1-FFL with AND logic is a pulse generator and also speeds response compared to an unregulated circuit.


  • When multiple factors regulate a single gene, we need to specify the logic of the regulation, usually OR or AND.

import numpy as np
import scipy.integrate

import biocircuits

import bokeh.io
import bokeh.plotting

import colorcet

import panel as pn


colors = colorcet.b_glasbey_category10
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