6. Robustness in biological circuits¶
The on-delay of the C1-FFL is robust to changes in the ratio of the Hill activation constants, \(\kappa\), in the regime when \(\kappa\) is order one or greater.
Exact adaptation, such as that displayed by the chemotaxis circuit in E. coli, can be achieved through integral feedback.
Michaelis-Menten kinetics to model enzyme dynamics.
import numpy as np import scipy.integrate import biocircuits import bokeh.io import bokeh.plotting import panel as pn pn.extension() bokeh.io.output_notebook()